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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC1 All Species: 28.48
Human Site: T596 Identified Species: 56.97
UniProt: Q9H1A4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A4 NP_073153.1 1944 216500 T596 D P V H N R V T L E L S N G S
Chimpanzee Pan troglodytes XP_515601 1394 155989 T112 S E W N L F V T C L M N M M G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532958 1943 216470 T595 D P V C N R V T L E L S N G S
Cat Felis silvestris
Mouse Mus musculus P53995 1944 216068 T596 D P V H N R V T L E L S N G S
Rat Rattus norvegicus NP_001101241 1944 216060 T596 D P V H N R V T L E L S N G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419303 1945 216100 T598 D P V H N R V T L E L S S N T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921168 1979 220132 T596 D P V C N R V T L E L S S G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573025 2030 227256 T647 D P A G N R L T L V Y A T G R
Honey Bee Apis mellifera XP_001122449 1939 218025 L588 N C A R P P I L L E N P L V E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202400 910 100394
Poplar Tree Populus trichocarpa XP_002312165 1929 212815 S581 E K M D S F G S N M E G N R S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196175 1678 186257 Y396 G K Q C L C R Y V L P S W L G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 97.3 N.A. 92.1 92.9 N.A. N.A. 81.7 N.A. 66 N.A. 33.6 38 N.A. 25.2
Protein Similarity: 100 71.5 N.A. 98.5 N.A. 96 96.5 N.A. N.A. 90.2 N.A. 79 N.A. 52.2 59.1 N.A. 33.8
P-Site Identity: 100 13.3 N.A. 93.3 N.A. 100 100 N.A. N.A. 80 N.A. 86.6 N.A. 46.6 13.3 N.A. 0
P-Site Similarity: 100 33.3 N.A. 93.3 N.A. 100 100 N.A. N.A. 93.3 N.A. 93.3 N.A. 60 26.6 N.A. 0
Percent
Protein Identity: 28.5 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 9 0 25 0 9 0 0 9 0 0 0 0 0 0 % C
% Asp: 59 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 9 0 0 0 0 0 0 0 59 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 9 0 0 9 0 0 0 0 9 0 50 17 % G
% His: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 17 0 9 9 67 17 50 0 9 9 0 % L
% Met: 0 0 9 0 0 0 0 0 0 9 9 0 9 9 0 % M
% Asn: 9 0 0 9 59 0 0 0 9 0 9 9 42 9 0 % N
% Pro: 0 59 0 0 9 9 0 0 0 0 9 9 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 59 9 0 0 0 0 0 0 9 9 % R
% Ser: 9 0 0 0 9 0 0 9 0 0 0 59 17 0 50 % S
% Thr: 0 0 0 0 0 0 0 67 0 0 0 0 9 0 9 % T
% Val: 0 0 50 0 0 0 59 0 9 9 0 0 0 9 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _